Description

Agentis Longevity: Inside the National Platform Reshaping Longevity Medicine

Longevity medicine has moved from a niche interest among biohackers and the ultra-wealthy into a genuine growth category within American healthcare, and few companies illustrate that shift as clearly as Agentis Longevity. Launched in December 2024 with backing from Chicago-based private equity firm Shore Capital Partners, Agentis has grown quickly through a combination of clinic acquisitions and organic expansion, positioning itself as a national platform built specifically around helping patients understand, track, and actively manage their biological aging process, rather than simply treating disease after it appears.

What distinguishes Agentis from the broader wave of longevity-branded clinics and supplement companies is its structure: it’s not a product you order online, but a network of physician-led partner clinics offering hormone optimization, metabolic health management, cognitive performance support, and a range of advanced diagnostics, unified under a proprietary assessment called the Longevity Quotient, or LQ. As of its most recent public figures, Agentis operates through 14 partner clinics across more than 10 markets nationwide, having served over 3,300 patients, with more than $17 million in committed capital behind its growth.

In this article, we’ll take a research-based look at what Agentis Longevity actually is, how its signature Longevity Quotient assessment works, what services its partner clinics provide, and how the company has grown through a series of notable acquisitions and partnerships, including a 2026 collaboration with wearable health technology company Ultrahuman. We’ll also look honestly at the broader scientific and regulatory context surrounding longevity medicine, since this is a category that includes some well-established, evidence-based interventions alongside others that remain more experimental, and understanding that distinction matters for anyone considering this kind of care.

As with any medical service, the information in this article is intended to be informative rather than a substitute for a direct conversation with a qualified healthcare provider. Hormone optimization, peptide therapies, and other interventions offered through longevity clinics carry real physiological effects and potential risks, and are appropriate only following proper diagnostic evaluation by a licensed physician, not as a self-directed wellness purchase.

What is Agentis Longevity?

Agentis Longevity is a healthcare services platform, headquartered in Nashville, Tennessee, built around acquiring and supporting independent longevity and performance medicine clinics across the United States. Rather than operating as a single clinic or a direct-to-consumer product company, Agentis functions more like a growth platform in the private equity sense: it partners with, and in many cases acquires, established longevity practices, then provides the operational infrastructure, capital, and shared clinical standards needed to help those practices expand while maintaining physician-led care at the local level.

The company was launched in December 2024 by Shore Capital Partners, with veteran healthcare operator Jimmy St. Louis named as CEO. St. Louis previously founded Regenerative Medicine Solutions and AlliRx, and served as COO of Laser Spine Institute, giving him direct prior experience building and scaling healthcare service businesses before taking on the Agentis role. St. Louis has also spoken publicly about a personal connection to the mission, coming from what he’s described as a medical family and framing Agentis’s purpose around the idea that quality of life and length of life should go hand in hand.

Since its launch, Agentis has grown primarily through acquisition, bringing established longevity and men’s health practices into its platform, including Mantality, a Midwest-based provider specializing in testosterone replacement therapy and medical weight loss with clinics across Missouri, Iowa, Wisconsin, Nebraska, Michigan, Ohio, and Pennsylvania; BioDesign, a Florida-based longevity and men’s performance clinic group with locations in Tampa, Orlando, Lake Mary, and Melbourne; and Arete Wellness, a Nashville-based practice bringing a team of more than 45 traveling nurses and medical professionals along with an existing client roster that includes professional athletes and entertainers.

Today, Agentis describes itself as covering eleven distinct clinical pillars across its partner clinic network: longevity medicine, detoxification support, stress and resilience, gut health, hormone health, metabolic health, cardiovascular care, cognitive performance, inflammation management, sleep and recovery, and personalized nutrition. The company holds Great Place to Work® certification and continues to describe itself as actively expanding its clinical footprint nationwide.

How Does the Longevity Quotient (LQ) Assessment Work?

At the center of Agentis’s clinical model is the Longevity Quotient, or LQ, a proprietary scoring system the company describes as synthesizing multiple health measurements into a single number intended to reflect where a patient’s biological age stands relative to their chronological age. Rather than relying on a single blood test or a single risk factor, the LQ is built from five core components: a comprehensive blood panel, an InBody body composition scan, a cognitive function test, a grip strength measurement, and a broader cardiometabolic risk assessment.

The process begins with an in-person assessment at a partner clinic, which the company states requires no physician referral. During a single visit, patients complete the full panel of tests that feed into their LQ score. From there, a provider reviews the results directly with the patient and uses them as the foundation for a personalized care plan, which may address hormone optimization, metabolic health, cognitive performance, or a combination of these areas depending on what the assessment reveals.

In March 2026, Agentis announced a partnership with Ultrahuman, a wearable and metabolic health technology company known for its continuous glucose monitor (the Ultrahuman M1 CGM) and broader biosensor platform. This partnership is designed to feed continuous, real-time data, including glucose trends and recovery metrics, directly into a patient’s LQ score, moving the assessment from a single-visit snapshot toward something closer to an ongoing, updated picture of a patient’s health trajectory between clinic visits. According to the companies, this integration is intended to help close a well-documented gap in preventive care: patients often leave a check-up motivated, only to have that momentum fade once daily life, poor sleep, missed workouts, and stress resume, with no mechanism connecting the clinical snapshot to what’s actually happening day to day.

It’s worth noting that a composite health score like the LQ, while a useful organizing framework for a care plan, is not itself a validated diagnostic tool in the way a specific lab value or FDA-cleared diagnostic test is, and should be understood as a clinical decision-support tool used by a licensed provider rather than a standalone medical verdict.

Services Offered Through Agentis Partner Clinics

Agentis’s partner clinics provide a range of services that fall generally into diagnostic, hormone-related, metabolic, and broader wellness categories. Understanding what each of these involves, and what level of evidence supports them, is important context for anyone evaluating this kind of care.

Hormone Optimization and Testosterone Replacement Therapy

Hormone health, including testosterone replacement therapy (TRT) for men and broader hormone optimization protocols, represents one of the platform’s most established clinical service lines, reflected in its acquisition of Mantality, a practice specifically known for patient-first TRT care. TRT for men with clinically diagnosed hypogonadism, confirmed through repeated lab testing and clinical symptoms rather than lab values alone, is a well-established, evidence-based treatment with decades of clinical use. It’s important to note that appropriate candidacy depends on an actual diagnosis established through bloodwork and clinical evaluation, not simply a desire to feel more energetic or improve performance, and hormone therapy carries real risks and monitoring requirements that should be managed by a qualified physician.

Metabolic Health and Weight Management

Metabolic health services, including body composition tracking, glucose stability monitoring, and weight management support, are described as core offerings across the Agentis network. This category includes evidence-based approaches to managing conditions like insulin resistance and obesity-related metabolic risk, an area of medicine that has seen substantial recent clinical advancement, particularly with GLP-1-based medications, though the specific inclusion of these medications in Agentis’s protocols would depend on individual clinic offerings and a patient’s specific diagnostic workup.

Diagnostic Testing and Biosensor Integration

Comprehensive lab panels, body composition scanning, cognitive testing, and grip strength assessment form the diagnostic backbone of the LQ system, now enhanced through the Ultrahuman partnership’s continuous glucose and recovery data. This diagnostic-first approach reflects a broader trend in longevity medicine toward using objective, repeatable measurements to guide care rather than relying solely on symptom reporting.

Cardiovascular, Cognitive, and Inflammation-Focused Care

Beyond hormone and metabolic services, Agentis clinics offer early cardiovascular risk detection that goes beyond standard cholesterol panels, including markers like endothelial function and detailed lipoprotein analysis when clinically indicated, alongside cognitive performance support addressing attention, memory, and processing speed through sleep, vascular, and metabolic interventions rather than generic cognitive exercises. Inflammation management is addressed by tracing chronic inflammatory patterns back to their source, whether immune, gut, metabolic, or environmental, before addressing them in order of clinical impact.

Peptide Therapy and Regenerative Treatments

Agentis’s original 2024 launch announcement specifically referenced peptides and stem cells among the innovative therapies planned across its platform. This is an area of longevity medicine that warrants particular caution and context: peptide therapies and stem cell-based treatments occupy a more regulatory gray area than hormone replacement or standard diagnostic testing. Many peptides used in wellness and longevity settings are compounded rather than FDA-approved for the specific indications they’re used for, and stem cell treatments marketed for anti-aging or regenerative purposes have drawn specific FDA warnings in recent years regarding unapproved products and unsubstantiated claims. Anyone considering peptide or regenerative therapy through any provider, including an Agentis partner clinic, should ask specifically about the regulatory status of the substances being used, request clear information about the evidence supporting a specific protocol for their specific condition, and treat this category with a meaningfully higher degree of scrutiny than more established interventions like diagnosed-hypogonadism TRT.

Across all of these service lines, Agentis emphasizes what it describes as an “operating discipline” of clear protocols, repeatable lab testing, and physician-led oversight, intended to apply the same clinical rigor across its growing network of partner clinics rather than allowing standards to vary significantly by location.

Growth, Acquisitions, and Industry Context

Agentis’s growth trajectory reflects a broader wave of private equity investment moving into the longevity healthcare space. Since its December 2024 launch, the company has completed a steady sequence of acquisitions: Mantality in early 2025, expanding its hormone therapy and medical weight loss footprint across the Midwest; BioDesign in February 2026, adding four Florida locations and specific expertise in men’s performance medicine, with BioDesign co-founder Jeremy Avner joining Agentis in a clinical leadership role; and Arete Wellness, a Nashville-based practice bringing concierge recovery and performance services along with an established roster of professional athlete and entertainer clients.

Industry analysts have pointed to genuine market tailwinds behind this growth. The global hormone replacement therapy market was valued at approximately $37.4 billion in 2024, with continued growth projected as aging populations and rising rates of chronic, age-related conditions drive demand for hormone-related and metabolic care. At the same time, broader survey data cited in coverage of the Ultrahuman partnership suggests a meaningful gap between interest and action in preventive health: despite considerable public interest in longevity-focused care, only around 39% of U.S. adults regularly pursue preventive measures like comprehensive screenings, and fewer than 30% of people interested in longevity topics are actively discussing them with their own physician. This gap between curiosity and actual clinical engagement is part of what platforms like Agentis are explicitly positioning themselves to close.

Chris Mioton, a Partner at Shore Capital, has described the opportunity behind Agentis’s launch as tied to the early-stage growth of the consumer longevity market and the potential to build a national leader by combining clinical rigor with strategic marketing and operational scale. Whether that scale-focused, PE-backed growth model translates into consistently high clinical standards across every acquired practice is something patients evaluating any individual Agentis partner clinic should assess on its own merits, including checking the specific credentials and track record of the physicians at that particular location.

Who is Agentis Longevity’s Care Model Designed For?

Agentis positions its services broadly around adults interested in proactive, preventive health management rather than waiting for a specific diagnosis to prompt medical attention. Based on its service lines and clinical focus, a few groups stand out as particularly aligned with what the platform offers.

Men experiencing symptoms consistent with declining testosterone, including fatigue, reduced muscle mass, or changes in mood and libido, represent a core audience, particularly given the platform’s specific strength in TRT through its Mantality and BioDesign acquisitions. As noted earlier, appropriate candidacy for this treatment depends on confirmed lab-based diagnosis rather than symptoms alone.

Adults managing metabolic health concerns, including those interested in structured weight management support paired with detailed body composition and metabolic testing, are another clear fit, particularly given the platform’s emphasis on repeatable lab tracking over time rather than a single intervention.

Executives, athletes, and performance-focused individuals looking for a data-driven approach to sleep, recovery, cognitive performance, and stress resilience, particularly those interested in wearable-integrated tracking through the Ultrahuman partnership, represent a growing segment of the platform’s target audience, reflected in Arete Wellness’s existing roster of professional athlete and entertainer clients.

Anyone specifically interested in newer or more experimental interventions like peptide therapy or regenerative treatments should approach this category, at any provider, with a clear understanding of the current regulatory landscape and evidence base, discussed in more detail above, rather than assuming all services offered under a “longevity medicine” umbrella carry equivalent scientific support.

Considerations Before Choosing a Longevity Clinic

Longevity and performance medicine is a fast-growing but still relatively young category of care, and choosing any provider in this space, including an Agentis partner clinic, benefits from the same due diligence you’d apply to any medical decision. Confirm the credentials and licensing of the physician overseeing your specific care plan, since a company’s overall growth and investor backing doesn’t substitute for the qualifications of the individual provider you’ll actually be working with. Ask direct questions about the evidence base behind any specific recommended treatment, particularly for less-established interventions like peptides or regenerative therapies, and be wary of any protocol presented as universally beneficial regardless of your specific diagnostic results.

It’s also worth understanding that composite scores like the Longevity Quotient, while a genuinely useful way to organize a broad set of health data into an actionable care plan, are a clinical tool developed and used by a specific company, not an independently validated diagnostic standard recognized across the medical field. A good provider should be able to explain clearly which specific findings within your assessment are driving which specific recommendations, rather than treating the composite score itself as the entirety of the diagnostic picture.

Finally, cost is a meaningful factor to clarify upfront. Longevity and concierge-style medicine, including comprehensive diagnostic panels and hormone therapy, often falls outside standard health insurance coverage and can represent a significant out-of-pocket expense. Confirming pricing, what’s included in an initial assessment versus ongoing care, and any subscription or membership structure directly with your local partner clinic before committing is a reasonable and necessary step, since pricing can vary by location and is not uniformly published across the Agentis network.

Conclusion

Agentis Longevity represents a notable example of how private equity capital and physician-led clinical practice are converging around the growing consumer interest in longevity and preventive medicine. Through a combination of strategic acquisitions, including Mantality, BioDesign, and Arete Wellness, and a technology partnership with Ultrahuman aimed at connecting clinical assessment to real-time biosensor data, the company has built a genuinely broad platform spanning hormone health, metabolic care, cognitive performance, and diagnostic testing across a growing national footprint of partner clinics.

The strength of the evidence behind Agentis’s service lines varies meaningfully by category. Hormone optimization for diagnosed conditions and structured metabolic health management rest on considerably more established clinical ground than newer offerings like peptide therapy or regenerative treatments, which remain part of a more experimental, less uniformly regulated corner of the longevity medicine field. Anyone considering care through Agentis, or any longevity-focused clinic, should approach the decision the way they would any medical choice: verifying the credentials of the specific provider involved, asking pointed questions about the evidence behind any recommended protocol, and treating a composite wellness score as a useful starting point for conversation with a physician rather than a final verdict on their health.

As the longevity medicine category continues to mature and attract further investment, platforms like Agentis are likely to keep shaping how this kind of preventive, data-driven care gets delivered at scale. For patients genuinely interested in a more proactive, measurement-based approach to their long-term health, that can be a meaningful development, provided the underlying clinical rigor keeps pace with the platform’s growth.

Agentis Longevity FAQs

1. What is Agentis Longevity?
Agentis Longevity is a national healthcare platform that partners with and acquires physician-led longevity and performance medicine clinics across the United States.

2. Who founded Agentis Longevity?
Agentis was launched in December 2024 by Shore Capital Partners, with healthcare operator Jimmy St. Louis serving as CEO.

3. What is the Longevity Quotient (LQ)?
The LQ is Agentis’s proprietary health scoring system, combining bloodwork, body composition, cognitive testing, grip strength, and cardiometabolic risk into a single measure of biological age.

4. Do I need a referral to get assessed at an Agentis partner clinic?
No, the company states no physician referral is required to schedule a Longevity Quotient assessment.

5. What services does Agentis offer?
Services span eleven clinical pillars, including hormone health, metabolic health, cardiovascular care, cognitive performance, sleep and recovery, gut health, and personalized nutrition, along with hormone optimization, TRT, and peptide therapies depending on the specific clinic.

6. How many clinics does Agentis operate?
As of its most recent public figures, Agentis operates through 14 partner clinics across more than 10 markets nationwide.

7. What is the Ultrahuman partnership?
Announced in March 2026, this partnership integrates Ultrahuman’s wearable and continuous glucose monitoring data directly into a patient’s Longevity Quotient score for ongoing, real-time tracking.

8. Is testosterone replacement therapy through Agentis clinics evidence-based?
TRT for clinically diagnosed hypogonadism, confirmed through lab testing and clinical evaluation, is a well-established treatment; appropriateness depends on individual diagnosis by a licensed physician.

9. Are peptide and stem cell treatments offered through Agentis FDA-approved?
Many peptide and regenerative treatments in this space are not FDA-approved for the specific uses they’re marketed for; patients should ask specific providers about the regulatory status of any recommended treatment.

10. Is longevity care through Agentis covered by insurance?
Longevity and concierge-style medicine, including comprehensive diagnostics and hormone therapy, often falls outside standard insurance coverage; confirm costs directly with your local partner clinic.

11. What companies has Agentis acquired?
Agentis has acquired Mantality, BioDesign, and Arete Wellness as part of its national expansion strategy.

12. How do I find an Agentis partner clinic near me?
You can search current partner clinic locations directly through the official Agentis Longevity website.